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Resources Clinicians and patients should educate themselves using reputable clinical resources and choose providers that prioritize informed consent and individualized care
The MOTS-c peptide research is particularly relevant here, as MOTS-c affects mitochondrial function and exercise capacity in ways that could complement the metabolic effects of retatrutide
Get in the kitchen: Avoiding processed and ultra-processed foods
Currently, two ongoing clinical trials are investigating the role of GLP-1 RAs in IBD management, that would lead to further knowledge: a French study (ID NCT05196958) evaluating the safety and efficacy of GLP-1 RAs in treatment of DM2 in overweight IBD patients (115), and an American study (ID NCT06774079) comparing the efficacy of GLP-1 RAs tirzepatide versus diet in CD patients (116)
In addition, studies have shown that it also has a certain protective effect on reducing the incidence of cardiovascular disease in some high-risk groups